Quantitative study of diffusion kurtosis imaging in Parkinson disease with dysosmia
10.19845/j.cnki.zfysjjbzz.2022.0272
- VernacularTitle:扩散峰度成像在伴嗅觉障碍帕金森病患者的定量研究
- Author:
Huiqin SUN
1
;
Shengjie BAI
1
Author Information
1. Xuzhou Central Hospital,Xuzhou 221009,China
- Publication Type:Journal Article
- Keywords:
Parkinson disease;
Magnetic resonance imaging;
Diffusion kurtosis imaging;
Dysosmia;
Neurodegenerative diseases
- From:
Journal of Apoplexy and Nervous Diseases
2022;39(12):1086-1090
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the microstructure changes of brain regions of interest in patients with Parkinson disease with dysosmia using diffusion kurtosis imaging.Methods DKI scanning was performed in 16 patients with dysosmia and 21 patients without dysosmia.Supramarginal gyrus,postcentral gyrus,heschl gyrus and inferior temporal gyrus were selected as regions of interest.Results The values of FA,KFA,AK and RK in the region of interest in the Parkinson disease group with dysosmia were significantly lower than those without dysosmia (P<0.05);the values of AD,MD and RD in the region of interest in the Parkinson disease group with dysosmia were significantly higher than those without dysosmia (P<0.05);There was a close correlation between the olfactory score and the right supramarginal gyrus,postcentral gyrus,inferior temporal gyrus,bilateral heschl gyrus in the Parkinson disease group with dysosmia (P<0.05).Conclusion DKI parameters can be used as biomarkers for early diagnosis of dysosmia in Parkinson disease.
- Full text:2024071822082857422Quantitative study of diffusion kurtosis imaging in Parkinson disease with dysosmia.pdf
