Relationship between left ventricular mass index and left ventricular myocardial work index in patients with end －stage renal disease with preserved ejection fraction
10.19405/j.cnki.issn1000-1492.2023.03.022
- Author:
Tingting Wu
1
;
Xiang Xie
1
;
Fan Jiang
1
;
Sihua Fang
1
Author Information
1. Dept of Ultrasound，The Second Affiliated Hospital of Anhui Medical University，Hefei 230601
- Publication Type:Journal Article
- Keywords:
pressure-strain loop;
left ventricular mass index;
end-stage renal disease;
myocardial work index
- From:
Acta Universitatis Medicinalis Anhui
2023;58(3):481-485
- CountryChina
- Language:Chinese
-
Abstract:
Objective :To quantitatively evaluate the left ventricular myocardial work index (MWI) of patients with end-stage renal disease (ESRD) with preserved ejection fraction using left ventricular pressure-strain loop (PSL) ， and group them according to left ventricular mass index( LVMI) ，in order to compare the effect of different LVMI levels on left ventricular MWI．
Methods:81 patients with stage 5 chronic kidney disease，including 43 males and 38 females，were divided into left ventricular hypertrophy group ( LVH group) ( n = 44) and non-left ventricular hypertrophy group (NLVH group) ( n = 37) according to LVMI，and 37 healthy people matched in age and sex with the ESRD groups were randomly selected as the control group．The general clinical data，conventional echocardiographic parameters，global longitudinal strain ( GLS) ，and MWI namely global work index ( GWI) ，global constructive work ( GCW) ，global wasted work ( GWW) and global work efficiency ( GWE) of the three groups were compared．The correlation between MWI and various parameters were analyzed，and the independent predictors of MWI were analyzed too.
Result :The results showed that there were no significant differences in age，gender，height，weight and other general clinical data as well as left ventricular ejection fraction ( LVEF) among the three groups．In two ESRD groups，GWW was higher than that in control group，GWE was lower than that in control group，and were more significant in LVH group (P＜0. 05) ．LVMI was positively correlated with GWW，and negatively correlated with GWE ，respectively ，with specific independent correlation．
Conclusion:GWW and GWE can detect early impairment of left ventricular systolic function in ESED patients，and myocardial function impairment in LVH group is more serious than that in NLVH group．LVMI is an independent positive factor of GWW and an independent negative factor of GWE.
- Full text:2024071719064149626射血分数保留的终末期肾病患...数与左室心肌做功指数的关系_伍婷婷.pdf
