Changes in corneal epithelial thickness and optical density and their correlation after smart pulse technology-assisted transepithelial photorefractive keratectomy
10.3980/j.issn.1672-5123.2024.8.24
- VernacularTitle:SPT辅助的TPRK术后角膜上皮厚度和光密度的变化及两者的相关性
- Author:
Shiyang NIU
1
;
Hua YANG
1
;
Yan LI
1
;
Zhiqiang DAI
1
;
Xinmin LI
1
;
Yulan ZHOU
1
;
Ouyang ZHANG
1
;
Baojun WANG
1
Author Information
1. Department of Ophthalmology,the First Affiliated Hospital of Xinxiang Medical University, Weihui 453000, Henan Province, China
- Publication Type:Journal Article
- Keywords:
transepithelial photorefractive keratectomy(TPRK);
smart pulse technology(SPT);
corneal epithelial thickness;
corneal epithelial healing;
corneal optical density;
refractive error
- From:
International Eye Science
2024;24(8):1308-1313
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To evaluate the changes in corneal epithelial thickness(CET)and corneal optical density(CD)after smart pulse technology(SPT)-assisted transepithelial photorefractive keratectomy(TPRK)and analyze their correlation.METHODS: The prospective study included 60 patients(120 eyes)with myopia and myopic astigmatism who underwent SPT-TPRK in the ophthalmology department at the First Affiliated Hospital of Xinxiang Medical University between February and August 2023. Changes in CET and CD were evaluated preoperatively and at 1 wk, 1 and 3 mo postoperatively.RESULTS: A total of 14 cases(28 eyes)were lost to follow-up, and 3 patients(6 eyes)with postoperative haze were excluded from this study, resulting in a final inclusion of 43 patients(86 eyes). At 1 wk after SPT-TPRK, CET had statistically significantly thickened compared to preoperative levels(P<0.05), particularly in the CET at 0-2 mm central corneal area(P<0.05). At 1 mo after SPT-TPRK, the CET at 0-2 mm area had statistically significantly decreased(P<0.05). At 3 mo after SPT-TPRK, the CET at 0-2 mm had essentially reached preoperative levels. Postoperative CD values increased, with a positive correlation between CET in the 0-2 mm area and CD in the whole 0-2 mm area(r=0.256, P<0.05), and a positive correlation between CET in the 2-5 mm area and CD in the anterior 2-6 mm area(r=0.319, P<0.05).CONCLUSION: Corneal epithelial remodeling takes 3 mo in areas within 2 mm of the central cornea; areas with thinner CET have faster postoperative corneal epithelial remodeling and greater thickening in the early postoperative period; CD increases in the early postoperative period compared to the preoperative value, and in some areas, there is a positive correlation between CET and CD value.
