The prediction of oxygenation index on clinical outcomes of adult community acquired pneumonia patients
10.19405/j.cnki.issn1000-1492.2023.11.026
- Author:
Yuqing Wan
1
;
Haoming Ye
1
;
Min Shao
1
Author Information
1. Dept of Critical Medicine , The First Afiliated Hospital of Anhui Medical University , Hefei 230022
- Publication Type:Journal Article
- Keywords:
community acquired pneumonia;
oxygenation index;
predictive factors;
death risk;
restricted cubic spline curve
- From:
Acta Universitatis Medicinalis Anhui
2023;58(11):1957-1961
- CountryChina
- Language:Chinese
-
Abstract:
Objective : To explore the predictive value of oxygenation index ( P/F) for clinical outcomes in adult
community acquired pneumonia (CAP) patients .
Methods : 493 patients with CAP eligible for inclusion were extracted from AHCCDM , and were divided into survival group ( n = 405 ) and death group ( n = 88) according to
whether they survived at discharge ; multivariate Logistic regression analysis was used to identify independent risk factors associated with hospitalization death in CAP patients ; the trend of changes in oxygenation index (P/F) and hospital mortality risk was evaluated using a restricted cubic spline ( RCS) curve .
Results : Multivariate Logistic
regression analysis found that independent risk factors affecting hospitalization death in CAP patients included acute and chronic health scores (Apache II score)( OR = 1 . 11 , 95% CI : 1 . 07 - 1 . 15 , P = 0. 02) , P/F ( OR = 1 . 70 ,95% CI : 1 . 03 - 2. 82 , P = 0. 04) , and hemoglobin (Hb) and HCO3- concentration P > 0. 05 , which were not statistically significant; restrictive cubic spline regression analysis found that there was a non⁃linear response relation ship between P/F and hospital mortality (non⁃linear test P < 0. 001) , and a P/F of 250 mmHg was the cutoff point for the hospital mortality association analysis . P/F < 250 mmHg , for every 1 mmHg increased in P/F , the risk of
in⁃hospital mortality was reduced by 1% , HR : 0. 99 (0. 99 - 1 . 00) , P < 0. 001 . P/F > 250 mmHg , there was no association between CAP patients and in⁃hospital mortality , HR : 1 . 00 ( 1 . 00 - 1 . 01) , P < 0. 001 , indicating that other factors played a dominant role .
Conclusion :A significantly reduced P/F has a high predictive value for mortality in patients with community⁃acquired pneumonia .
- Full text:2024071216522216522氧合指数对成人社区获得性肺炎患者临床结局的预测价值_万玉青.pdf
