Quantitative analysis of early lumbar disc degeneration in young adults by intravoxel incoherent motion in body diffusion-weighted imaging
10.3969/j.issn.1673-9701.2024.12.005
- VernacularTitle:体素内不相干运动扩散加权成像对青年腰椎间盘早期退变定量分析的研究
- Author:
Fang CHEN
1
,
2
;
Mingzhe HU
1
,
2
;
Hai WU
1
,
2
;
Yaomeng CHEN
1
,
2
;
Peipei ZHU
1
,
2
Author Information
1. Department of Imaging, Wenzhou People&rsquo
2. s Hospital, Wenzhou 325000, Zhejiang, China
- Publication Type:Journal Article
- Keywords:
Lumbar disc degeneration;
Pfirrmann grading;
IVIM-DWI;
Magnetic resonance imaging
- From:
China Modern Doctor
2024;62(12):24-27,36
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the predictive value of slow apparent diffusion coefficient(ADCslow),fast apparent diffusion coefficient(ADCfast)and perfusion fraction(f)value of intravoxel incoherent motion in body diffusion-weighted imaging(IVIM-DWI)sequence in early lumbar disc degeneration in young people.Methods The IVIM-DWI technique was used as quantitative magnetic resonance imaging for 120 patients(596 lumbar intervertebral discs)with lower back pain included in Wenzhou People's Hospital.The ADCslow,ADCfast and f values of all lumbar intervertebral discs were measured,and then they were divided into 3 groups according to the Pfirrmann grading standard.SPSS 20.0 statistical software was used to analyze the data.Results The ADCfast value has statistical significance in distinguishing the lumbar intervertebral discs of each group:The area under the curve(AUC)of the normal group vs.the early degenerative group was 0.766,with a sensitivity of 64.2%and a specificity of 78.5%;The AUC of the normal group vs.the mid to late stage degenerative group was 0.822,with a sensitivity of 67.9%and a specificity of 91.3%;The AUC of the early degeneration group vs.the middle and late stage degeneration group was 0.797,with a sensitivity of 62.1%and a specificity of 92.1%.The ADCslow value has statistical significance in distinguishing the lumbar intervertebral discs of each group:AUC=0.707 in the normal group vs.the early degenerative group,with a sensitivity of 83.6%and a specificity of 61.0%;The AUC of the normal group vs.the mid to late stage degenerative group was 0.701,with a sensitivity of 84.5%and a specificity of 58.6%;The AUC of the early degeneration group vs.the middle and late stage degeneration group was 0.668,with a sensitivity of 86.6%and a specificity of 51.0%.The f value cannot distinguish between different groups of lumbar intervertebral discs.Conclusion ADCslow and ADCfast of IVIM-DWI sequence have certain accuracy and specificity in distinguishing the early degeneration of lumbar intervertebral disc in young people,which provides a reliable basis for early clinical treatment.
