A Mini Overview of Isolation, Characterization and Application of Amniotic Fluid Stem Cells.
10.15283/ijsc.2015.8.2.115
- Author:
Shiva GHOLIZADEH-GHALEHAZIZ
1
;
Raheleh FARAHZADI
;
Ezzatollah FATHI
;
Maryam PASHAIASL
Author Information
1. Department of Molecular Medicine, School of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
- Publication Type:Review
- Keywords:
Amniotic fluid;
Amniotic fluid- stem cells;
Isolation;
Differentiation;
Tissue engineering
- MeSH:
Adult;
Amniotic Fluid*;
Cartilage;
Female;
Fetus;
Heart;
Humans;
Kidney;
Lung;
Mesenchymal Stromal Cells;
Nervous System;
Parturition;
Regeneration;
Stem Cells*;
Tissue Engineering
- From:International Journal of Stem Cells
2015;8(2):115-120
- CountryRepublic of Korea
- Language:English
-
Abstract:
Amniotic fluid represents rich sources of stem cells that can be used in treatments for a wide range of diseases. Amniotic fluid- stem cells have properties intermediate between embryonic and adult mesenchymal stem cells which make them particularly attractive for cellular regeneration and tissue engineering. Furthermore, scientists are interested in these cells because they come from the amniotic fluid that is routinely discarded after birth. In this review we give a brief introduction of amniotic fluid followed by a description of the cells present within this fluid and aim to summarize the all existing isolation methods, culturing, characterization and application of these cells. Finally, we elaborate on the differentiation and potential for these cells to promote regeneration of various tissue defects, including fetal tissue, the nervous system, heart, lungs, kidneys, bones, and cartilage in the form of table.
