Systematic review of therapeutic effect of taohua decoction on ulcerative colitis
10.3969/j.issn.1673-9701.2024.11.015
- VernacularTitle:桃花汤治疗溃疡性结肠炎疗效的系统评价
- Author:
Aiyangzi LU
1
,
2
;
Hui GAO
1
,
3
;
Haoran SHENG
4
;
Qiuhong GUO
4
Author Information
1. 1.Hebei University of Chinese Medicine, College of Pharmacy, Shijiazhuang 050000, Hebei, China
2. 2.Department of Chinese Medicine, Wuxi Hospital of Traditional Chinese Medicine, Wuxi 214100, Jiangsu, China
3. 3.2nd Department of Nephrology, Hebei Provincial Hospital of Traditional Chinese Medicine, Shijiazhuang 050100, Hebei, China
4. Hebei University of Chinese Medicine, College of Pharmacy, Shijiazhuang 050000, Hebei, China
- Publication Type:Journal Article
- Keywords:
Taohua decoction;
Ulcerative colitis;
Systematical review;
Meta analysis
- From:
China Modern Doctor
2024;62(11):63-68
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical efficacy of Taohua Decoction in treating ulcerative colitis.Methods Searching CNKI,Wanfang,Weipu,China Biomedical Database,PubMed,Web of science,and Cochrane library,Screening literature and collecting literature related information.Using Review Manager 5.3 to evaluate the risk of bias and systematically evaluate efficacy indicators.Results A total of 546 articles were retrieved,and 16 were eventually included after censoring and screening.Meta analysis showed that total clinical effective rate:RR=1.19,95%CI:1.14-1.24,P<0.001.Colonoscopy score:MD=-0.61,95%CI:-1.11--0.11,P=0.02.Tumor necrosis factor(TNF)-α:MD=-22.18,95%CI:-36.70--7.66,P=0.003.C-reactive protein:MD=-10.85,95%CI:-30.48-8.77,P=0.28.Incidence of adverse reactions:RR=0.40,95%CI:0.24-0.65,P<0.001.Conclusion The total clinical effective rate,colonoscopy score,TNF-α and incidence of adverse reactions of Taohua Decoction in treating ulcerative colitis was superior to that in the control group.There was no significant difference between Taohua Decoction and the control group in reducing C-reactive protein.
