Chromosomal karyotype analysis of peripheral blood in infertility patients with different semen quality
10.3969/j.issn.1673-9701.2024.11.009
- VernacularTitle:不同精液质量不育症患者的外周血染色体核型分析
- Author:
Huilin SUN
1
,
2
;
Jianbing LIU
1
,
2
;
Min LI
1
,
2
;
Jianli ZHENG
1
,
2
;
Jing WU
1
,
2
Author Information
1. Medical Genetic Center, the Affiliated Yancheng Maternity &
2. Child Health Hospital of Yangzhou University, Yancheng 224001, Jiangsu, China
- Publication Type:Journal Article
- Keywords:
Male infertile;
Semen analysis;
Karyotype analysis;
Sex chromosomes
- From:
China Modern Doctor
2024;62(11):36-39
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the type and incidence of abnormal chromosome karyotype in peripheral blood of infertile patients with different semen quality.Methods Selectet 292 infertility patients who came to our hospital from January 2018 to December 2021 for G-banding karyotyping and semen analysis.According to the semen analysis results,the patients were divided into abnormal semen quality group and normal control group.We made statistics and analysis on the abnormal karyotypes.Results In the group with abnormal semen quality,20 cases(18.87%)of abnormal karyotypes were found.In the normal control group,9 cases(4.84%)had abnormal karyotypes were found.The comparison of the abnormal rates of peripheral blood chromosome karyotypes between the two groups showed statistical significance(P<0.05).The detection rate of chromosomal abnormalities in patients with Azoospermia was 50%,and sex chromosome abnormalities were the main types of abnormalities in this group.Conclusion Karyotype analysis of infertile patients can effectively analyze the causes of infertility,and has important clinical significance for assisted reproduction and primary prevention of birth defects.
