Meta-analysis of the association between late-life depression and mild cognitive impairment
10.3969/j.issn.1673-9701.2024.08.001
- VernacularTitle:老年抑郁与轻度认知障碍相关性的Meta分析
- Author:
Min WANG
1
;
Yuanyue LIU
2
;
Lei SHENG
2
Author Information
1. Department of Neurology, the Second Hospital Affiliated to Nanjing University of Traditional Chinese Medicine, Nanjing 210017, Jiangsu, China
2. Department of Neurology, Jiangsu Second Chinese Medicine Hospital, Nanjing 210017, Jiangsu, China
- Publication Type:Journal Article
- Keywords:
Elderly;
Depression;
Mild cognitive impairment;
Meta-analysis
- From:
China Modern Doctor
2024;62(8):1-5,11
- CountryChina
- Language:Chinese
-
Abstract:
Objective To systematically evaluate the correlation between elderly depression and mild cognitive impairment.Methods We searched the CNKI,VIP,WanFang Data,Cochrane Library,EMbase,Pubmed,and Web of Science databases using computer,and collected cohort studies on the correlation between elderly depression and mild cognitive impairment.The search time limit was from the establishment of the database to July 6,2023.Two researchers independently completed the literature screening,data extraction,and quality evaluation,and conducted a Meta-analysis using Review Manager 5.4 software.Results A total of 10 articles were included,with a total sample size of 26 813 people.The Meta-analysis showed that there was a correlation between elderly depression and mild cognitive impairment(OR=1.47,95%CI:1.25-1.72,P<0.001).Conclusion Current evidence indicates that elderly depression is one of the risk factors for the development of mild cognitive impairment.This conclusion is limited by the type,quality,and quantity of research,and needs to be validated by more high-quality research.
