Clinical study of Guishao Liujunzi Decoction with TCM mouthrinse for the treatment of Hp-associated gastritis
10.3969/j.issn.1673-9701.2024.05.017
- VernacularTitle:归芍六君子汤联合中药漱口治疗耐药Hp相关性胃炎的疗效观察
- Author:
Lifan TIAN
1
;
Chunlin WANG
2
;
Yiping ZHANG
2
;
Lei YE
1
;
Jiangyan LI
1
Author Information
1. Department of TCM, Quzhou Hospital of TCM Affiliated to Zhejiang Chinese Medical University, Quzhou 324002, Zhejiang, China
2. Intensive Care Unit, Quzhou Hospital of TCM Affiliated to Zhejiang Chinese Medical University, Quzhou 324002, Zhejiang, China
- Publication Type:Journal Article
- Keywords:
Hp-associated gastritis;
Guishao Liujunzi Decoction;
TCM mouthrinse;
Drug resistance
- From:
China Modern Doctor
2024;62(5):78-81
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy of Guishao Liujunzi Decoction combined with traditional Chinese medicine(TCM)mouthrinse in the treatment of helicobacter pylori(Hp)associated gastritis,and its effect on the Hp conversion rate.Methods Eighty patients with Hp-related gastritis were selected and randomly divided into the control group(standard quadruple therapy)and the treatment group(standard quadruple therapy combined with Guishao Liujunzi Decoction and TCM mouthrinse),with 40 patients in each group.The clinical efficacy,TCM syndrome scores,and Hp conversion rate of the two groups were observed.Results The total effective rate of the treatment group(95%)was higher than that of the control group(72.5%)(P<0.05).The Hp conversion rate in the treatment group(90%)was higher than that in the control group(72.5%)(P<0.05).After treatment,the main symptom scores and total scores of the two groups decreased compared to before treatment,and the treatment group was lower than the control group(P<0.05).Conclusion The combination of modified Guishao Liujunzi decoction and TCM mouthrinse in the treatment of Hp-related gastritis can significantly improve clinical efficacy and Hp negative conversion rate compared to conventional treatment.