Application of contrast-enhanced ultrasound in evaluating skeletal muscle microcirculation in patients with type 2 diabetes mellitus
10.3969/j.issn.1673-9701.2024.05.008
- VernacularTitle:超声造影在2型糖尿病患者骨骼肌微循环病变评估中的应用
- Author:
Pengfei WANG
1
,
2
;
Manjing YE
1
,
2
;
Maosheng XU
1
,
2
;
Chunpeng ZOU
1
,
2
;
Yanyan DONG
1
,
2
Author Information
1. Department of Ultrasound, the 2nd Affiliated Hospital and Yuying Children&rsquo
2. s Hospital of WMU, Wenzhou 325000, Zhejiang, China
- Publication Type:Journal Article
- Keywords:
Contrast-enhanced ultrasound;
Type 2 diabetes mellitus;
Skeletal muscle;
Microcirculation
- From:
China Modern Doctor
2024;62(5):35-39
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of contrast-enhanced ultrasound(CEUS)in the assessment of diabetic microangiopademia through evaluating microcirculation perfusion of triceps surae muscle by CEUS.Method Totally 51 patients with type 2 diabetes mellitus(T2DM)admitted in our hospital between August 2020 and January 2023 were collected,including 15 pure T2DM patients and 36 T2DM patients complicated with microcirculatory disturbance(T2DM+CM).Each patient's hemoglobin A1c(HbA1c)and homeostatic model assessment for insulin resistance(HOMA-IR)were recorded.After getting enhanced intensity(PI-BI)and regional peak time(TTP-AT)by CEUS,comparative analysis between groups was conducted.Results The levels of HbA1c and HOMA-IR in T2DM+CM group were higher than those in pure T2DM group(P<0.05).TTP-AT in T2DM+CM group were longer than that in pure T2DM group of all muscles musculi gastrocnemii(MG),laterale musculi gastrocnemi(LG),soleus(SOL)and triceps surae muscle's junction region)(P<0.05).The TTP-AT of SOL was longest in both groups,followed by LG,and MG(P<0.05).The PI-BI had no significant difference among MG,LG and SOL in pure T2DM group.The PI-BI of MG was higher than that of SOL in the T2DM+CM group(P<0.05).TTP-AT of triceps surae muscle's junction region had significant positive association with both HbA1c and HOMA-IR(P<0.05).Conclusion The TTP-AT of triceps surae muscle measured by CEUS is a new indicator for evaluating microangiopathopathy in T2DM patients.
