Effect of endoscopic hemostasis combined with octreotide on hemodynamics and clinical outcome of patients with acute upper gastrointestinal bleeding
10.3969/j.issn.1673-9701.2023.35.010
- VernacularTitle:内镜下止血联合奥曲肽对急性上消化道出血患者的血流动力学及临床疗效的影响
- Author:
Xia HU
1
;
Dinghua ZHANG
;
Hongjuan YANG
Author Information
1. 江西省新余银河医院内三科,江西新余 338000
- Keywords:
Acute upper gastrointestinal bleeding;
Endoscopic hemostasis;
Mr Qu peptide;
Hemodynamics;
Clinical curative effect
- From:
China Modern Doctor
2023;61(35):42-45
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of endoscopic hemostasis combined with octreotide on hemodynamics and clinical outcome of patients with acute upper gastrointestinal bleeding.Methods From January 2019 to June 2022,80 patients with acute upper gastrointestinal bleeding in Xinyu Yinhe Hospital of Jiangxi Province,and according to random number table method,40 cases each in the control group and 40 cases in the observation group.The control group was treated with conventional endoscopic,while the observation group was treated with octreotide on this basis.The clinical efficacy,high sensitivity C-reactive protein(hs-CRP),cortisol(Cor)levels and hemodynamic changes[cardiac output(CO),heart rate(HR),mean arterial pressure(MAP)]were compared between the two groups.Results The total effective rate of the observation group was significantly higher(P<0.05).After treatment,hs-CRP and Cor levels in 2 groups were lower than before,and hs-CRP and Cor levels in observation group were significantly lower(P<0.05).After treatment,the levels of CO,HR and MAP in the two groups were decreased,and the levels of CO,HR and MAP in the observation group were significantly lower(P<0.05).Conclusion Endoscopic hemostasis combined with octreotide can promote the hemodynamic indexes of patients with acute upper gastrointestinal bleeding to return to normal,improve the levels of hs-CRP and Cor,and improve clinical efficacy.
