Clinical effect analysis of ritodrine and atosiban in the treatment of cervical insufficiency after emergency cervix cerigation
10.3969/j.issn.1673-9701.2023.35.004
- VernacularTitle:紧急宫颈环扎术后使用利托君及阿托西班治疗宫颈机能不全的临床疗效分析
- Author:
Yuanying CUI
1
;
Fangting YE
;
Xiying WU
;
Jingzhen YANG
;
Mei LI
Author Information
1. 赣州市妇幼保健院妇产科,江西赣州 341000
- Keywords:
Emergency cervical cerclage;
Litojun;
Atosiban;
Cervical incompetence;
Neonatal outcomes
- From:
China Modern Doctor
2023;61(35):13-16
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical efficacy of using rituximab and atoxiban in the treatment of cervical incompetence after emergency cervical cerclage surgery.Methods Sixty patients with cervical incompetence admitted from May 2020 to February 2022 were selected as the study subjects.Divide into control group A,control group B,and trial group C using random number table method,with 20 cases in each group.All three groups underwent emergency cervical cerclage surgery.After the surgical treatment,control group A received treatment with rituximab hydrochloride,control group B received treatment with atoxiban,and experimental group C received treatment with atoxiban on the basis of rituximab hydrochloride.Analyze and compare the inhibitory effects of uterine contractions,incidence of adverse reactions,and neonatal outcomes among three groups.Results The inhibition rate of uterine contractions in control group A and test group C was higher than that in control group B(P<0.05);The incidence of postoperative complications in experimental group C was lower than that in control group A and control group B,with a statistically significant difference(P<0.05);Compared with control group A and control group B,the incidence of fetal loss,neonatal asphyxia,and low birth weight infant outcomes in experimental group C was not statistically significant(P>0.05).Compared with control group A and control group B,experimental group C had a longer gestational week extension and a higher Apgar score for newborns,with statistically significant differences(P<0.05).Conclusion The combination treatment of rituximab and atoxiban after emergency cervical cerclage surgery for this disease has good effects,can better inhibit uterine contractions,appropriately prolong gestational age,improve neonatal outcomes and prognosis,and reduce adverse drug reactions in pregnant women.
