Diagnostic value of transcranial substantia nigra ultrasound in Parkinson's disease and analysis of clinical characteristics of patients with different substantia nigra echoes
10.3969/j.issn.1673-9701.2023.34.016
- VernacularTitle:经颅黑质超声在帕金森病中的诊断价值及不同黑质回声患者的临床特征分析
- Author:
Meixia ZHANG
1
;
Lu QIAO
;
Shuyun HU
Author Information
1. 宜春市中医院超声医学科,江西宜春 336000
- Keywords:
Parkinson's disease;
Transcranial substantia nigra ultrasound;
Diagnostic value;
Substantia nigra echo;
Clinical characteristics
- From:
China Modern Doctor
2023;61(34):60-62,99
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the diagnostic value of transcranial substantia nigra ultrasound in Parkinson's disease(PD)and the clinical characteristics of patients with different substantia nigra(SN)echoes.Methods Sixty patients with PD admitted to Yichun Hospital of Traditional Chinese Medicine from October 2020 to January 2023 were included in study group,and another 60 normal persons who received health examination in our hospital during the same period were included in control group.Both groups were examined by transcranial substantia nigra ultrasound.The SN high-echo area and ratio of total area of hyperechoic substantia nigra to total area of mesencephalon(S/M)of two groups were compared,and the positive rate of PD diagnosed by transcranial substantia nigra ultrasound was calculated.According to the intensity of SN echo,PD patients were divided into PD-SN-group and PD-SN+ group,and the clinical characteristics of patients with different SN echo were compared.Results The SN high-echo area and S/M of study group were significantly higher than those of control group(P<0.05).Transcranial substantia nigra ultrasound showed PD-SN-in 10 cases and PD-SN+ in 50 cases.The positive rate of PD diagnosed by transcranial substantia nigra ultrasound was 83.33%(50/60).There were statistically significant differences between PD-SN+ group and PD-SN-group in gender,age,H-Y stage,age of onset,score of mini mental status examination and score of Montreal cognitive assessment(P<0.05).Conclusion Transcranial substantia nigra ultrasound can better help clinical screening and detection of PD,and improve the positive detection rate of PD.
