Evaluation of the value of ultrasound elastography combined with serum markers in the assessment of chronic hepatitis B fibrosis
- VernacularTitle:超声弹性成像联合血清标志物评估慢性乙肝纤维化的价值评价
- Author:
Haiping ZHOU
1
;
Yanhua HUANG
;
Xiaobo TU
;
Lidan XIE
Author Information
1. 浙江省丽水市中心医院超声科
- Keywords:
Ultrasound elastography;
Serum markers;
Chronic hepatitis B;
Fibrosis
- From:
China Modern Doctor
2019;57(10):119-122
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the value of ultrasound elastography combined with serum markers in the assessment of chronic hepatitis B fibrosis. Methods 100 patients with chronic hepatitis B liver fibrosis who were diagnosed and treated in our hospital from January 2015 to December 2017 were randomly selected. All patients were given hepatic histopathological tests, serological tests, and ultrasound elastography. The liver biopsy results were taken as the final diagnosis results. The accuracy of classification of hepatitis B fibrosis by the combined diagnosis of ultrasound elastography and serum markers was observed. Results The total accuracy of the combined examination was 91.00％ with histological examination as the final results. There was no statistically significant difference between the results of the two examinations (P>0.05). The ultrasound elastography score and FIB4 score in the patients with hepatitis B fibrosis grade F1-F4 were increased along with the increase of grade, and there was statistically significant difference (P<0.05). Conclusion Ultrasound elastography combined with serum markers has an important clinical value in the assessment of the degree of chronic hepatitis B fibrosis. It is non-invasive, easy to operate and highly accurate, and can provide a reliable basis for disease diagnosis and staging.
