Effect of disease course on the cognitive function and related risk factors in the elderly patients with type 2 diabetes
- VernacularTitle:病程对老年2型糖尿病患者认知功能及相关危险因素的影响
- Author:
Zheli CHEN
1
;
Lin NI
;
Xinhua SHEN
;
Lilei LEI
;
Wanqiu NA
;
Xin'gen PAN
;
Ke CHEN
;
Weiliang HE
Author Information
1. 浙江省湖州市第三人民医院精神科
- Keywords:
Type 2 diabetes;
Cognitive function;
Alzheimer's disease;
Risk factors
- From:
China Modern Doctor
2019;57(10):90-94
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of disease course on cognitive function and related risk factors in elderly patients with type 2 diabetes. Methods A total of 193 patients with type 2 diabetes were selected and divided into 4 groups according to the course of disease, the new diagnosis group, the group of the course of disease within 1 year, the group of the course of disease between 1-5 years and the group of the course of disease over 5 years. The general clinical features, biochemical indicators and neuropsychological test scores among the groups were compared.Results Age (P=0.024), treatment methods (P<0.001), and total cholesterol (P=0.037) were significantly different among the groups of different courses of disease. Logistic regression analysis using cognitive dysfunction as a dependent variable revealed that the course of diabetes (OR=1.205, 95％CI=1.128-1.286) and medical treatment (OR=2.931, 95％CI=1.067-8.053) was associated with cognitive dysfunction. Conclusion There is a cognitive dysfunction in the elderly patients with type 2 diabetes, and the course of diabetes is an important risk factor.
