Therapeutic effect of children's growth patch combined with recombinant human growth hormone in treatment of idiopathic short stature
- VernacularTitle:儿童生长贴联合重组人生长激素治疗特发性矮小症的疗效
- Author:
Lingzhi ZHU
1
;
Jinyan RU
;
Huijun YU
;
Jianmin YE
;
Xiufang CHEN
;
Haiying FENG
Author Information
1. 台州恩泽医疗中心(集团)路桥医院儿童生长发育科
- Keywords:
Children's growth patch;
Recombinant human growth hormone;
Idiopathic short stature;
Height growth
- From:
China Modern Doctor
2019;57(10):59-61,65
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the therapeutic effect of children's growth patch combined with recombinant human growth hormone on idiopathic short stature. Methods A retrospective analysis of 45 children patients with idiopathic short stature from February 2016 to February 2017 was carried out, according to the treatment method, they were divided into the control group, the observation group 1 and the observation group 2, with 15 cases in each group. The control group was those who rejected all medications. The observation group 1 was those who were given children's growth patch; the observation group 2 was those who were given growth patch combined with recombinant human growth hormone therapy. The treatment lasted for 12 months. The height growth, genetic height, and predicted adult height were compared. Results The control group, the observation group 1 and the observation group 2 were compared, and the height growth values were (3.87±1.25) cm, (7.93±1.53) cm, and (10.20±1.97) cm, respectively, and the difference was significant (F=59.48, P<0.01); the genetic heights were (156.80±4.94) cm, (156.07±3.97) cm, (156.13±4.58) cm, respectively, and the difference was not significant (F=0.12, P>0.05); the predicted adult heights were (155.73±3.31) cm, (164.80±5.24) cm, and (167.87±5.68) cm, respectively, and the difference was significant (F=25.35, P<0.01). Conclusion Children's growth patch combined with recombinant human growth hormone in the treatment of idiopathic short stature can significantly increase the height growth value and increase the predicted value of adult height.
