Correlation between TG, HDL-C, TC and diabetic peripheral neuropathy
- VernacularTitle:TG、HDL-C、TC与糖尿病周围神经病变的相关性研究
- Author:
Fang WAN
1
;
Lingling CAO
;
Fei SUN
Author Information
1. 江西省九江市第一人民医院内分泌科
- Keywords:
Triglyceride (TG);
High density lipoprotein cholesterol (HDL-C);
Total cholesterol (TC);
Type 2 diabetes;
Peripheral neuropathy;
Correlation
- From:
China Modern Doctor
2018;56(35):37-39
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the correlation between Triglyceride (TG), high density lipoprotein cholesterol (HDL-C), total cholesterol (TC) and diabetic Peripheral neuropathy, and to provide a clinical basis for the diagnosis of diabetic peripheral neuropathy. Methods A total of 48 patients with diabetic peripheral neuropathy diagnosed in our hospital from January 2017 to January 2018 were retrospectively analyzed and enrolled into the DPN group. Another 48 patients with type 2 diabetes admitted to our hospital during the same period were included in the T2DM group. The differences of triglyceride (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C),low density lipoprotein cholesterol (LDL-C),and apolipoprotein B (ApoB) between the two groups were analyzed. And the correlation between these indicators and diabetic peripheral neuropathy were analyzed by logistic regression equation. Results The levels of TG, TC, LDL-C and ApoB in the DPN group were significantly higher than those in the T2DM group, and HDL-C was significantly lower in the DPN group than that in the T2DM group (P<0.05). Logistic regression equation analysis showed that TG, TC, and HDL-C, LDL-C, ApoB were risk factors for the onset of DPN (P<0.05). Conclusion The level of blood lipids in patients with diabetic peripheral neuropathy is higher than that in patients with diabetes alone. The levels of TG, TC and HDL-C,LDL-C, ApoB are closely related to the pathogenesis of DPN, which are important factors leading to neuromicrovascular disease.
