Application of non-invasive ventilator combined with compound ipratropium bromide inhalation in acute exacerbation of chronic obstructive pulmonary disease
- VernacularTitle:无创呼吸机联合复方异丙托溴铵雾化吸入在慢阻肺急性加重期中的应用
- Author:
Qin WANG
1
;
Xiaohong HUANG
;
Qiqi ZHU
Author Information
1. 江西省九江市第一人民医院老年科
- Keywords:
Chronic obstructive pulmonary disease;
Acute exacerbation;
Non-invasive ventilator;
Compound ipratropium bromide;
Aerosol inhalation therapy
- From:
China Modern Doctor
2018;56(15):91-93,97
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of non-invasive ventilator combined with compound ipratropium bromide inhalation in the acute exacerbation of chronic obstructive pulmonary disease. Methods 60 patients with acute exacerbation of chronic obstructive pulmonary disease were included in this study. Data were collected from March 2013 to March 2017. Participants were randomly and equally divided into observational group and control group. The control group was given routine treatment such as relieving cough and reducing sputum, anti-infection, etc. On the basis of control group, the observation group was given combined with non-invasive ventilator combined with compound ipratropium bromide inhalation therapy. The hospitalization time, APACHE Ⅱ score, tracheal intubation status of the two groups were compared and analyzed. Results The results showed that after different treatments there were 8 cases of tracheal intubation in the control group and 3 cases in the observation group, and the tracheal intubation rate was statistically different(P＜0. 05). In addition, there was no significant difference in partial pressure of oxygen, partial pressure of carbon dioxide and APACHE Ⅱ score between the two groups before treatment, while the difference was significant after treatment, and the length of hospitalization was also statistically significant (P＜0. 05). Conclusion In the treatment of patients with acute exacerbation of chronic obstructive pulmonary disease, a non-invasive ventilator combined with compound ipratropium bromide on the basis of routine treatment can effectively shorten the hospital stay, improve the patient's oxygen partial pressure, and the overall treatment effect is significant, which deserve promotion.
