Efficacy and prognosis of breast conserving surgery for triple negative breast cancer in women ≤35 years
- VernacularTitle:保乳手术对≤35岁女性三阴性乳腺癌的疗效及预后探讨
- Author:
Qi LI
1
;
Minhua WU
;
Weizhu WU
Author Information
1. 宁波市医疗中心李惠利东部医院甲乳外科
- Keywords:
Female triple negative breast cancer;
Breast conserving surgery;
Complications;
Prognosis
- From:
China Modern Doctor
2018;56(15):54-56,60
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect and prognosis of breast conserving surgery on triple-negative breast cancer patients ≤35 years old. Methods 60 cases of ≤35-year-old triple negative breast cancer from July 2011 to July 2016 in our hospital were selected as the observation group. Other 60 triple-negative breast cancer patients who underwent modified radical mastectomy from July 2011 to July 2016 at the same period were selected as control group. The surgical observation index, complications, local recurrence, distant metastasis and 1-year survival rate between the two groups were compared. Results The operation time of the observation group was significantly shorter than that of the control group, and the difference was significant(P＜0. 05). The intraoperative blood loss in the observation group was significantly less than that of the control group. There was significant difference between the two groups (P＜0. 05). The incidence of postoperative complications in the observation group was significantly less than that in the control group. There was significant difference between the two groups (6. 67％ vs 20. 00％, P＜0. 05). Among them, there were 2 cases of subcutaneous effusion, 2 cases of flap ischemia in the observation group. And there were 3 cases of subcutaneous effusion, 3 cases of ischemic skin flap and 6 cases of upper limb swelling in the affected side in the control group. The follow-up of 1 year showed that the local recurrence rate and distant metastasis rate in the observation group was significantly lower than that in the control group. There was significant difference between the two groups (P＜0. 05). However, there was no significant difference in one-year survival rate between the two groups (98. 33％ vs 83. 33％, P＞0. 05). One case died in the observation group and died of brain metastases at 11 months after operation. Two patients in the control group died of liver metastases at 6 months and 12 months after operation. Conclusion Breast-conserving surgery for triple-negative breast cancer patients ≤35 years has definite effect, which can significantly reduce postoperative recurrence and distant metastasis and improve the success rate of operation.
