Pathological analysis of six cases of multilocular cystic renal cell carcino-ma patients
- VernacularTitle:6例多房性囊性肾细胞癌的病理分析
- Author:
Chunyi REN
1
;
Hongli LIAO
;
Liya CHEN
;
Haibo YU
Author Information
1. 浙江省温州市中心医院病理科
- Keywords:
Multi-cystic renal cell carcinoma;
Pathological features;
Distinguishment and diagnosis;
Prognosis
- From:
China Modern Doctor
2015;53(35):103-105,109
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the pathological features, distinguishment and diagnosis and prognosis of multiple cystic renal cell carcinoma. Methods Six patients with multilocular cystic renal cell carcinoma in our hospital from 2007 to 2010 were chosen and reviewed for analysis. All patients who were found to have mass after physical examina-tion, came to our hospital, and image examination was conducted, and pathological detection and immunohistochemical detection were conducted after surgical resection. All the results were recorded. After hospitalization, all patients were followed up for a period of five years, and prognosis was recorded. Results Among 6 cases of multilocular cystic renal cell carcinoma patients, there were three cases of male patients and three cases of female patients. Pathological exami-nation revealed the apparent limits of diseased region and normal part, the surface coating, no vascular invasion, and no metastasis. The average tumor diameter was (3.52士0.48) cm, and different cysts of varying sizes were visible in section, with visible bloody or serous liquid in cavities. Microscopic examination showed clear cell of monolayers lining in cysts, partially with papillary structures, and there were inflammatory cells in interval composed of fibrous tissue. Tumor cells included translucent pulp and stained chromatin. According to fuhrman nuclear grade, 5 patients were grade Ⅰ, and 1 patients was gradeⅡ. Immunohistochemical detections such as Vim and EMA were strongly positive, and CD68 and CD10 were negative. Six patients had no recurrence within 5 years, and 5-year survival rate was 100%, with good prog-nosis. It should be noted that multi-cystic renal cell carcinoma and other renal cystic diseases should be identified. Conclusion Pathological features of multi-cystic renal cell carcinoma are unique, and we should pay attention to iden-tification of multi-cystic renal cell carcinoma and other renal cystic diseases. The prognosis of multi-cystic renal cell carcinoma is good.
