Curative effect of lactoferrin on rotavirus enteritis in children
- VernacularTitle:乳铁蛋白治疗儿童轮状病毒肠炎疗效分析
- Author:
YanLi WANG
1
;
Yuanju DU
;
Chunli LI
Author Information
1. 郑州市第一人民医院儿科
- Keywords:
Rotavirus;
Enterits;
Children;
Lactoferrin
- From:
China Modern Doctor
2015;53(35):74-76
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of lactoferrin in treatment of rotavirus enteritis in children. Methods Stool samples were collected from 210 children who were hospitalized in the department of peadiatric, the First people's Hospital of Zhengzhou from September 2013 to March 2014. Enzyme linked immunosor-bent assay (ELISA) was used to detect rotavirus antigen. The 118 positive samples were randomly divided into observation group and control group. 59 cases in each group. Control group was treated with the fluid infusion, microecologics, dietary adjustment etc, while the observation group received lactoferrin on the basis of the same treatment as control group. The curative rate, time of the symptoms alleviated, length of the hospitalizationa and adverse reactions of the two groups were compared. Results The total effective rate of observation group was 94.9%(56/59), which was higer than 72.9%(43/59) of control group. The difference had statistical diftference(P<0.05). The curative rate, time of the symptoms alleviated, length of the hos-pitalization of the observation were superior than the control group, there were no serious adverse reactions of the two groups. Conclusion Lactoferrin has exact effect in the treatment of children with rotavirus enteritis,and with less ad-verse reaction.
