Clinical efficacy of different statins in the treatment of primary hyperlipi-demia
- VernacularTitle:不同他汀类药物治疗原发性高脂血症的临床疗效研究
- Author:
Fengju ZHANG
1
;
Yongliang XUE
Author Information
1. 河南大学第一附属医院老年科
- Keywords:
Osuvastatin;
Primary hyperlipidemia;
Cholesterol;
Low-density lipoprotein
- From:
China Modern Doctor
2015;(22):100-102
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the different statins in the treatment of elderly patients with primary hyperlipidemia. Methods A total of 76 patients with primary hyperlipidemia admitted in our hospital from January 2013 to November 2014 were randomly divided into two groups. For 39 cases in the observation group, chose rosuvastatin treatment; for 37 cases in the control group, chose the atorvastatin treatment. Two groups of patients were observed and compared in the clinical efficacy, the degree of improvement in various lipid levels and the incidence of adverse reactions. Results The rate of excellent clinical efficacy in the observation group was 92.3%, significantly better than that was the 70.3%in the control group,the difference was statistically significant(P<0.05);The degree of improvement in lipid levels in the observation group was bigger than that in the control group,the difference was statistically significant(P<0.05);inflam-mation factor of the observation group was lower than that in the control group, the difference was statistically signifi-cant(P<0.05). Conclusion The clinical efficacy of rosuvastatin treatment of primary hyperlipidemia is good,can effec-tively improve lipid levels in patients, reduce inflammation in the body concentration factor, deserves in clinical prac-tice.
