The effect of pidotimod on henoch-schonlein purpura in children
- VernacularTitle:匹多莫德治疗儿童过敏性紫癜疗效评价
- Author:
Yuzhou LU
1
;
Xiaowei LIU
Author Information
1. 广西壮族自治区钦州市第一人民医院儿科
- Keywords:
Pidotimod;
Henoch-schonlein purpura;
Immunologic function
- From:
China Modern Doctor
2015;(21):48-50
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the effect of pidotimod in children's henoch-schonlein purpura. Methods A total of 90 cases of patients were divided into two groups:experimental group (n=45) and control group (n=45). The experimen-tal group was treated with pidotimod combined conventional treatment while the control group was treated with deslanoside. The time for eliminating the clinical symptoms, the levels of IgG, IgA, IgM and T lymphocyte were com-pared. Results (1) The time for eliminating the dinical symptoms and the hospital stays in experimental group were obviously shortened than those in control group(P<0.01). The recurrence rates of rash in experimental group were lower than those in control group(P<0.05). (2)Before treatment, the levels of IgG,IgA,IgM and T lymphocyte had no signifi-cant difference in two groups (P>0.05); After treatment, the levels of IgA and CD8+ in experimental group were lower than that of control group, while the level of IgG, IgM CD4+ and CD4+/CD8+ in experimental group were higher than those of control group ( P<0 . 05 ) . ( 3 ) The recurrence rates in experimental group were lower than those in control group(P<0.05). Conclusion Pidotimod combined conventional treatment show curative effect on henoch-schonlein pur-pura which provides significant information for clinical treatment.
