Application study of MATRICS consensus cognitive battery in first-episode schizophrenia patients
- VernacularTitle:精神分裂症认知功能成套测验在首发精神分裂症患者中的应用研究
- Author:
Mingrong YAO
1
;
Jianbo HU
Author Information
1. 浙江省嘉兴康慈医院精神科
- Keywords:
MATRICS consensus cognitive battery;
First-episode schizophrenia;
Cognitive;
Profile analysis
- From:
China Modern Doctor
2015;(21):14-17,20
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the characteristics of cognitive function in patients with the first-episode and chronic schizophrenia. Methods 83 cases of first-episode schizophrenia patients, 77 cases of chronic schizophrenia patients and 75 healthy volunteers from January 2013 to June 2014 were selected. MATRICS consensus cognitive battery (MCCB) test was conducted on them and their cognitive profile patterns and characteristics of cognitive function impairment were analyzed. Results Compared with the healthy control group, the first-episode schizophrenia patients and chronic schizophrenia patients got hurt in psychomotor speed, attention, working memory, verbal learning and memory, visual learning and memory, reasoning and problem solving ability, social cognition and other areas in the MCCB (P<0.05). There were differences in comparing working memory and social cognition of the first-episode schizophrenia patients and chronic schizophrenia patients (P<0.05). Conclusion The first-episode schizophrenia patients get less injury than chronic schizophrenia patients in the working memory and social cognition. Whether first-episode schizophrenia pa-tients or chronic schizophrenia patients, they are impaired compared with the normal population in cognitive function.
