Observation of the efficacy for different doses of Liptor on serum lipid,carotid atherosclerosis of elderly hypertensive patients
- VernacularTitle:不同剂量立普妥对老年高血压患者血脂、颈动脉粥样硬化的疗效观察
- Author:
Jing XU
1
;
Xiaoguang LIU
;
Mingxing ZHAO
;
Zejun LIU
;
Lingyun WANG
Author Information
1. 第二炮兵总医院礼士路门诊部内二科
- Keywords:
Liptor;
Elderly hypertension;
Dyslipidemia;
Carotid atherosclerosis plaque
- From:
China Modern Doctor
2015;(19):96-99
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy for different doses of Liptor on serum lipid ,carotid atherosclerosis of elderly hypertensive patients. Methods A total of 50 cases of elderly patients of Lishi Road community in the outpa-tient department for treatment of high blood pressure and carotid atherosclerosis from January 2012 to December 2013 were chosen as the research object.They were randomly divided into group A with 25 cases and group B with 25 cases. Patients in group A were given oral Liptor 10mg once daily and patients in group B were given oral Liptor 20 mg once daily. The carotid artery intima-media thickness,plaque block area and plaque score,serum HDL-C, LDL-C,TG,TC for the two groups before treatment and 6 months after treatment were compared. Results The carotid artery intima-media thickness,plaque block area and plaque score, serum HDL-C,LDL-C,TG,TC were not significantly different between the two groups 6 months after treatment (P>0.05). Conclusion No significant difference has been found in Liptor at doses of 10 mg/d or 20 mg/d on serum lipid,carotid atherosclerosis of elderly hypertensive patients.
