The impact observation of laparoscopic surgery for colon cancer serum TNF-α, TGF-β1 and IL-17
- VernacularTitle:腹腔镜结肠癌根治术对患者血清TNF-α、TGF-β1及IL-17的影响
- Author:
Zhaolei REN
1
Author Information
1. 淄博矿业集团有限责任公司中心医院普外科
- Keywords:
Elderly colon cancer;
Laparoscopic extended radical mastectomy;
Open extended radical mastectomy;
Tu-mor necrosis factor-α;
Transforming growth factorβ1;
Interleukin-17
- From:
China Modern Doctor
2015;(19):49-50,53
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate laparoscopic radical of serum TNF-α, TGF-β1 and IL-17 affects the surgery. Methods A total of 75 cases elderly colon cancer patients were divided into two groups according to surgical, control group (n=37) and the observation group (n=38), respectively, to expand the use of open and laparoscopic radical resec-tion extended radical mastectomy treatment. The intraoperative and postoperative conditions, serum TNF-α, TGF-β1 and IL-17 levels before and after surgery, quality of life scores before and after treatment were compared. Results (1)Surgical patients in the observation group time, blood loss, postoperative exhaust time and hospital stay were signifi-cantly lower than the control group (P<0.05); (2) 1 d postoperative serum TNF-α, TGF-β1 and IL-17 levels were sig-nificantly higher than before surgery (P<0.05), and the index levels of 5 d in observation group were significantly lower than control group after 5 d level, the differences were statistically significant (P<0.05). Conclusion Laparoscopic extended radical mastectomy and extended radical mastectomy can open an increase in serum TNF-α, TGF-β1 and IL-17 levels, but over time, the expansion of radical laparoscopic surgery in patients with serum gradually returned to the index preoperative level, but open extended radical mastectomy in patients with serum above indicators slow recovery;laparoscopic extended radical mastectomy can improve prognosis for patients.
