Correlation of serum BDNF and cognitive behavioral abnormalities in children with OSAHS
- VernacularTitle:阻塞性睡眠呼吸暂停低通气综合征患儿血清BDNF与认知行为异常的相关性
- Author:
Yaer CHEN
1
;
Miaoshang SU
Author Information
1. 浙江省诸暨市第四人民医院儿科
- Keywords:
Obstructive sleep apnea-hypopnea syndrome;
Cognitive behavioral;
Brain derived neurophic factor
- From:
China Modern Doctor
2015;(16):54-57
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss correlation of serum BDNF and cognitive behavioral abnormalities in children with OSAHS. Methods Sixty children with OSAHS from Jan 2013 to Oct 2014 were selected as subjects. Correlation of cog-nitive behavioral abnormalities and serum BDNF was analyzed. Results Conners score of OSAHS group was higher than the control group(P<0.01);cognitive behavioral abnormalities rates of OSAHS group was higher(P<0.01). Serum BD-NF of OSAHS group was lower than control group than the control group(P<0.01). Serum BDNF of cases with cognitive behavioral abnormalities of OSAHS group was lower than cases without cognitive behavioral abnormalities (P<0.01). Serum BDNF of OSAHS was negative with conners score (r=-0.866,P<0.01). Conclusion Cognitive behavioral abnor-mality is negative with serum BDNF in children with OSAHS.
