The preventive effect research of dezocine in the treatment of hyperpathia caused by remifentanil and sevoflurane
- VernacularTitle:地佐辛对瑞芬太尼复合七氟醚麻醉致痛觉过敏的预防效果探究
- Author:
Li XU
1
;
Xiaoyong ZHU
;
Shengjie YAO
Author Information
1. 浙江萧山医院麻醉科
- Keywords:
Dezocine;
Hyperpathia;
Fentanyl;
Remifentanil;
Sevoflurane
- From:
China Modern Doctor
2015;(15):108-111
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the preventive effect research of dezocine in the treatment of hyperpathia caused by remifentanil and sevoflurane. Methods A total of 84 epigastric operation patients were collected into this study. Both of them were anesthetized by the therapy of remifentanil and sevoflurane. Patients of observation group were treated with dezocine before the end of the operation. Patients in control group were treated with fentanyl before the end of the operation. The six behavioral pain score (BRS6) and VAS score were used to evaluate the degree of pain in patients before and after surgery, and recovery time, extubation time and leave PACU time as well as anesthesia ad-verse reactions in the two groups were recorded. Results The differences of preoperative BRS6 and VAS score were not statistically significant (P>0.05), BRS6 and VAS scores at 1 h after surgery in the observation group were significantly lower than the control group; recovery time, extubation time and leave PACU time in observation group were (28.96±5.54) min, (21.08±7.45) min and (58.05±10.32) min, while (38.62±5.05) min, (57.08±5.36) min and (69.05±9.52) min in the control group, the differences were statistically significant (P<0.05); 1d after anesthesia, incidence of vomiting in the observation group was significantly lower than the control group (P<0.05). Conclusion Dezocine has perfect preven-tive effect in the treatment of hyperpathia caused by remifentanil and sevoflurane.
