A clinical comparative study on two types of intermittent noninvasive me-chanical ventilation and continuous noninvasive mechanical ventilation in the treatment of typeIIrespiratory faiture
- VernacularTitle:两种间歇无创机械通气与持续无创机械通气治疗Ⅱ型呼吸衰竭的临床对比研究
- Author:
Dong WANG
1
;
Guodi SHEN
;
Ying TAN
;
Lan XU
Author Information
1. 浙江省湖州市中心医院急诊科
- Keywords:
Type II ventilatory failure;
Noninvasive mechanical ventilation;
Removal of ventilator;
Blood-gas analysis;
Complications
- From:
China Modern Doctor
2015;(15):79-82
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the clinical effects and safety of different ratios of intermittent noninvasive mechanical ventilation and continuous noninvasive mechanical ventilation in the treatment of typeIIrespiratory failure. Methods A total of 94 patients with acute attack of chronic obstructive pulmonary disease complicated with type II respiratory fail-ure were selected. They were randomly assigned to intermittent group A of 32 patients, intermittent group B of 31 pa-tients and continuous group of 31 patients. They received 3:1 intermittent noninvasive mechanical ventilation, 1:1 inter-mittent noninvasive mechanical ventilation and continuous intermittent noninvasive mechanical ventilation respectively on the basis of regular treatment. Results The pH value, PaO2 and PaCO2 in the three groups in 6 h, 24 h and 72 h after treatment were all significantly different with those before treatment (P<0.05). The pH value, PaO2 and PaCO2 in 24 h and 72 h after treatment were all significantly different with those in 6 h after the treatment (P<0.05). The pH val-ue, PaO2 and PaCO2 in 72 h after treatment were all significantly different with those in 24 h after the treatment (P<0.05). The pH value, PaO2 and PaCO2 in the three groups before the removal of ventilator, 6 h and 12 h after the removal were not significantly different (P>0.05). Duration of mechanical ventilation in intermittent group A and intermittent group B were both significantly lower than those in the continuous group (P<0.05). Incidences of flatulence, tracheal intubation, ventilator-associated pneumonia and facial pressure sores in intermittent group A and intermittent group B were all sig-nificantly lower than those in the continuous group (P<0.05). Conclusion The two intermittent ratios of noninvasive me-chanical ventilation and continuous noninvasive mechanical ventilation have similar effects as the removal of ventilator. Intermittent mechanical ventilation is able to obviously shorten the duration of mechanical ventilation and hospitaliza-tion time, and lower the incidence of complications. 1:1 intermittent noninvasive ventilation has the optimal safety, which is considered to be the ideal choice of noninvasive mechanical ventilation.
