Curative effects of quadruple therapy containing compound allantoin in the treatment of chronic gastritis infected with helicobacter pylori
- VernacularTitle:含复方尿囊素四联疗法治疗幽门螺杆菌感染慢性胃炎的疗效
- Author:
Jiansong FANG
1
;
Jianming SHAO
;
Jiafei YAN
Author Information
1. 浙江省浦江县人民医院内一科
- Keywords:
Helicobacter pylori;
Chronic gastritis;
Compound allantoin;
Quadruple therapy
- From:
China Modern Doctor
2015;(15):17-20
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical effects of quadruple therapy containing compound allantoin in the treat-ment of chronic gastritis infected with helicobacter pylori. Methods A total of 90 patients with chronic gastritis infected with helicobacter pylori in our hospital from January 2011 to December 2012 were selected as research subjects. They were assigned to research group and control group according to the method of random number table. The control group was given regular quadruple therapy containing bismuth, and the research group was given quadruple therapy contain-ing compound allantoin. Clinical curative effects in the two groups were observed. Results The effective rate of clinical treatment and negative conversion rate of helicobacter pylori in the research group were 91.1%and 86.7%, and the dif-ferences compared with those of 88.9% and 82.2% in the control group were not statistically significant (P>0.05); inci-dence of adverse effects in the research group was 6.7%, lower than that of 22.2% in the control group, and the differ-ence was statistically significant between the two groups (P<0.05). Drug tolerance degree in the research group was significantly higher than that in the control group (P<0.05), and the difference was statistically significant. Conclu-sion Clinical application of quadruple therapy containing compound allantoin in the treatment of chronic gastritis in-fected with helicobacter pylori is feasible. It is able to effectively reduce adverse effects, improve drug tolerance and is worthy of clinical application.
