Lipoprotein-associated phospholipase A2 and ischemic stroke
- VernacularTitle:脂蛋白相关磷脂酶A2与缺血性脑卒中的研究进展
- Author:
Bangxian XU
1
;
Yuanfei DENG
Author Information
1. 北京大学深圳医院特诊老年病科
- Keywords:
Lipoprotein-associated phospholipaseA2;
Ischemic stroke;
Atherosclerosis;
Inflammation biomarker
- From:
China Modern Doctor
2015;(14):152-155,160
- CountryChina
- Language:Chinese
-
Abstract:
Atherosclerosis is the leading cause of ischemic stroke. As a new inflammation biomarker, lipoprotein-asso-ciated phospholipaseA2 (Lp-PLA2) is largely associated with the development of atherosclerosis and plaque vulnerability. It has been recognized that Lp-PLA2 plays crucial roles on assessing the risk stratification and recurrent risk of is-chemic stroke, and may be a unique prediction factor. This review is going to summarize the relevant data about the biochemical characteristics of Lp-PLA2, the action of Lp-PLA2 on atherosclerosis and the association with carotid atherosclerotic and ischemic stroke.
