The impact of limbal stem cell transplantation in the treatment of ptery-gium on the tear film function in patients with type 2 diabetes mellitus
- VernacularTitle:角膜缘干细胞移植治疗翼状胬肉对2型糖尿病患者泪膜功能的影响
- Author:
Shuxia LI
1
;
Huiyi DUAN
Author Information
1. 北京市昌平区医院眼科
- Keywords:
Limbal stem cells;
Pterygium;
Tear film function;
Type 2 diabetes mellitus
- From:
China Modern Doctor
2015;(14):64-66
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the impact of limbal stem cell transplantation in the treatment of pterygium on the tear film function in patients with type 2 diabetes mellitus. Methods All 70 cases of primary pterygium patients with type 2 diabetes mellitus in Beijing Changping district Hospital from January 2012 to December 2014 were chosen. Basal tear secretion, tears river area and tear film break-up time of their two eyes were measured. Excision of ptery-gium combined with limbal stem cell transplantation was conducted. Basal tear secretion,tears river area and tear film break-up time before surgery, two weeks and two months after surgery were measured respectively, and the impact of limbal stem cell transplantation in the treatment of pterygium on the tear film function in patients with type 2 diabetes mellitus was analyzed. Results The differences of preoperative Schirmer test and tear river area of two eyes were not statistically significant(P>0.05),and the difference of preoperative tear film break-up time of two eyes was statistical-ly significant(P<0.05). The differences of the operative eyes Schirmer test and tears river area before and after surgery were not statistically significant(P>0.05),and the difference of preoperative and postoperative tear break-up time was statistically significant (P<0.05). Conclusion The tear film after the limbal stem cell transplantation in the treatment of pterygium is more stable than that before surgery, and the limbal stem cell transplantation can improve tear film function in patients with type 2 diabetes mellitus.
