Relationship between blood pressure variability rate and extent of critically in ill patients with sepsis
- VernacularTitle:脓毒症患者血压变异率与病情危重程度的关系研究
- Author:
Zhirong NG ZHA
1
;
Qiang LI
Author Information
1. 浙江中医药大学附属第一医院重症医学科
- Keywords:
Sepsis;
Blood pressure variation rate;
Degree in critical condition;
Correlation;
HDL-C
- From:
China Modern Doctor
2015;(14):4-6,10
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the Relationship between blood pressure variability rate and extent of critically in ill patients with sepsis. Methods From May 2012 to April 2013 in our hospital, 60 cases of sepsis patients for the study were divided into APACHE-II≥20 points(critical group)and APACHE-II<20 minutes(non-critical group), selected the same period to our hospital for medical examination of 30 cases of healthy subjects (control group). The risk and non-risk reorganization reorganization patients 24 h SBP-CV,24 h DBP-CV,dSBP-CV,dDBP-CV,nSBP-CV, nDBP-CV mutation rate, mutation rate and blood pressure APACHE-II score correlation analysis. Comparison of the three groups of patients with high-density protein cholesterol (HDL-C), low-density protein cholesterol (LDL-C), inter-leukin-6(IL-6),interleukin-18(IL-18)were compared. Results The danger of recombinant APACHE-II score was(29.56±0.79), non dangerous recombinant APACHE-II score was (13.15±0.58). Two groups of SBP mutation rate comparison, with statistically significant difference(P<0.05). Spearman analysis showed that 24 h SBP-CV,dSBP-CV,nSBP-CV,related to the mutation rate and APACHE-IIscore was positively(r=0.762,P=0.003). Critical group,non criti-cal group,control group HDL-C, LDL-C gradually increased, IL-6, IL-18 were lower, with statistically significant difference between the two groups (P<0.05). Conclusion The rate and blood pressure variability in the degree of sep-sis in critically ill patients was positively correlated, the mechanism may be the promotion of IL-6, inflammatory kookiness such as IL-18 secretion,and expand the inflammatory response.
