Influence of sulfentanyl on hemodynamics and stress reaction on patients with operations on cranium and brain during anesthesia induction period
- VernacularTitle:舒芬太尼对颅脑手术患者麻醉诱导期间血流动力学及应激反应的影响
- Author:
Haihua XU
1
;
Xuanyu SHENG
;
Haitao YU
;
Jianguo XIA
;
Jingbo PEI
Author Information
1. 杭州市萧山区中医院麻醉科
- Keywords:
Sulfentanyl;
Operations on cranium and brain;
Anesthesia induction period;
Hemodynamics;
Stress reac-tion
- From:
China Modern Doctor
2015;(13):118-121
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss influence of sulfentanyl on hemodynamics and stress reaction on patients with opera-tions on cranium and brain during anesthesia induction period. Methods A total of 100 cases of clinical information of patients with severe brain injury were divided into two groups in accordance with different anesthetic methods, with 50 cases in anesthesia group A (fentanyl as anesthetic method) and 50 cases in anesthesia group B (sulfentanyl as anesthetic method). The changes of MAP, HR, cortisol (Cor) in plasma and glucose (Glu) in blood before the anesthesia induction (T0), 2 minutes after anesthesia induction and before the trachea cannula (T1), 1 minute after the trachea cannula (T2), upon the incision of scalp (T3), upon the drilling of skull (T4), and upon the withdrawal of trachea cannu-la (T5) were observed. Results The MAP and HR of patients in anesthesia group B at T1, T2, T3, T4 and T5 were all lower than those in anesthesia group A (P<0.05). The Cor in plasma and Glu in blood of patients with severe brain injury in anesthesia group B at T2, T3, T4 and T5 were all lower than those in anesthesia group A(P<0.05). Conclusion Compared with fentanyl, the application of sulfentanyl on patients with severe brain injury has more favorable curative effect on hemodynamics and stress reaction during anesthesia induction period, which can maintain the circulatory sys-tem more stable, is more suitable for the anesthesia induction.
