The correlation between D-dimer and high sensitivity C reactive protein for elderly patients with coronary artery disease
- VernacularTitle:老年冠心病患者超敏C反应蛋白、D-二聚体的相关性研究
- Author:
Jianlan LI
1
Author Information
1. 浙江省荣军医院检验科
- Keywords:
Coronary heart disease;
High sensitivity C reactive protein;
D-dimer
- From:
China Modern Doctor
2015;(13):114-117
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between D-dimer and high sensitivity C reactive protein for elderly patients with coronary artery disease. Methods A total of 162 cases of elderly patients with coronary artery disease pa-tients were selected from internal geriatric department in our hospital, according to the classification, all patients were divided into stable angina pectoris (SAP group), coronary heart disease unstable angina pectoris (UAP group), non ST segment elevation myocardial infarction (NSTEMI group) and ST segment elevation myocardial infarction (STEMI group), all serum high sensitivity C reactive protein and D-dimer level were detected by immune turbidimetric method, the impact on clinical cardiovascular adverse events and the severity of coronary lesions (Gensini score) relationship were analyzed. Results High sensitive C reactive protein, D-dimer level of STEMI group single and combined detec-tion positive rate were significantly higher than SAP group, UAP group and NSTEMI group, the above indices of NSTE-MI group were significantly higher than SAP group and UAP group, the above indices of UAP group were significantly higher than SAP group with statistically significant differences between groups (P<0.05), the combined positive rate were significantly higher than single detection, compared with significance (P<0.05), clinical cardiovascular adverse events of high C levels group was significantly higher than low C group, high D group was significantly higher than low D group, compared with significant differences (P<0.05), the Pearson correlation analysis showed that, high sensitive C reactive protein and D-dimers were positively correlated (r=0.51, P=0.03), both of which were related to the Gensini score was positively(r=0.46, 0.52, P=0.04, 0.03). Conclusion High sensitivity C reactive protein, D-dimer are significant difference in different types of elderly coronary heart disease, both are positively correlated with the severity of coronary artery disease, and has an important role in the evaluation of occurrence of clinical adverse cardiovascular events.
