Clinical study of atomization inhalation with mixture of baikal skullcap root and lightyellow sophora root for proventing invasive fungal infections on lower respiratory tract infection after chemotherapy
- VernacularTitle:黄芩苦参合剂雾化吸入预防化疗后下呼吸道感染并发侵袭性真菌感染的临床研究
- Author:
Qun FANG
1
;
Xiangfu GAO
;
Xianghong MAO
;
Liming LOU
;
Lingling ZHANG
;
Fulan CHEN
;
Min LIN
;
Xiaoming CHEN
Author Information
1. 浙江中医药大学附属第三医院院感科
- Keywords:
Fungal infections;
Respiratory tract infection;
Radix scutellariae radix sophorae flavescentis mixture;
Noso-comial infection;
Elder
- From:
China Modern Doctor
2015;(12):102-105
- CountryChina
- Language:Chinese
-
Abstract:
[Abstratct] Objective To investigate the preventive effect of atomization inhalation with mixture of baikal skullcap root and light yellow sophora root for proventing invasive fungal infection on lower respiratory tract infection after chemotherapy. Methods A total of 60 cases of patients with lower respiratory tract infections after chemotherapy were selected and randomized into control groups and treatment groups, there were 30 cases in every group, anti-infection was taken in two groups according to drug sensitivity test,atomamdation inhalation with mixture of baikal skullcap root and light yellow sophora root was taken in treatment groups in addition, clinical effect was contrasted, incidence rate and time of fungal infection were contrasted between control group and treatment group,and index of blood gas analysis was contrasted between control group and treatment group after two weeks. Results Clinical efficiency was 86.67% in treatment group and was 70.00% in control group,clinical efficiency was higher in treatment groups than in control group,incidence rate of fungal infection was 6.67% in treatment group and was 23.33% in control group,incidence rate of fungal infection was lower in treatment group than in control goup,time of fungal infection was (11.58±1.31)days in treatment group and was (9.41±1.10)days in control group,time of fungal infect was later in treatment group than that in control group. There were no significant differences of the levels of pH,SaO2,PaCO2 and PaO2 between the two groups before treatment, the levels of pH,SaO2,and PaO2 were higher and PaCO2 was lower in treatment group than that in control goup after treatment. Conclusion Atomization inhalation with mixture of baikal skullcap root and light yellow sophora root could improve clinical curative effect of lower respiratory tract infection after chemotherapy,and im-prove respiratory function,provent invasive fungal infections and has good clinical effect.
