Therapeutic effect on treating chronic cervicitis by antibiotics combined with the local drugs
- VernacularTitle:抗生素联合局部用药治疗慢性宫颈炎的疗效观察
- Author:
Yubo SHI
1
;
Zhenzhong WANG
;
Tuanjie WANG
Author Information
1. 宁波市第一医院妇产科
- Keywords:
Chronic cervicitis;
Guizhifuling capsule;
Ceftriaxone sodium;
5％ potassium dichromate solution;
VEGF;
NKTs
- From:
China Modern Doctor
2015;(12):74-77
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the clinical efficacy between ceftriaxone sodium combined with 5% potassium dichromate solution and ceftriaxone sodium combined with Guizhifuling capsule which treated the chroniccervicitis re-spectively. Methods A total of 103 cases of chronic cervicitis were randomly divided into two groups,both were in cef-triaxone sodium intravenous infusion,1g/day/time. On the basis of continuous intravenous injected for 7 days,the control group involved 50 patients treated with ceftriaxone sodium combined with 5% potassium dichromate solution, once a month,two consecutive times for a course of treatment. The study group(53 cases)was treated with ceftriaxone sodium combined with Guizhifuling capsule by local administration,3 days/times,5 times for 1 course of treatment (15 days). The clinical efficacy of the two groups was observed after 3 months. The change of VEGF and NKTs in both groups of patients before and after treatment was observed, and the correlations were further analyzed. Results The cure rate of the control group was 42.0%,the total effective rate was 76.0%;the cure rate of the research roup was 47.2%,the to-tal effective rate was 90.6%,the difference was significant (χ2=3.96,P<0.05). Correlation analysis showed that VEGF was positively correlated with NKTs in different classification of patients with chronic cervicitis (P<0.05). After treat-ment, VEGF and NKTs between the two groups increased significantly. Compared with the control group, and there were significant differences between the two groups (P<0.05). Conclusion The clinical efficacy of ceftriaxone sodium combined with Guizhifuling capsule in local treatment of chronic cervicitis is better than that of ceftriaxone sodium combined with 5%potassium dichromate solution.
