Effect of anesthesia methods and depth on perioperative cellular immune function of gastric cancer patients
- VernacularTitle:麻醉方法及深度对胃癌患者围手术期细胞免疫功能的影响
- Author:
Kunhong YANG
1
Author Information
1. 湖北民族学院附属民大医院麻醉科
- Keywords:
Anesthesia methods;
Anesthesia depth;
Gastric cancer operation;
Cellular immune function
- From:
China Modern Doctor
2015;(11):125-127
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss effect of anesthesia methods and depth on perioperative cellular immune function of gastric cancer patients. Methods Sixty cases with gastric cancer treated by operation were randomly divided into in-halation anesthesia group and intravenous anesthesia group (each of 30 cases). Two groups were divided into deep anesthesia subgroup and light anesthesia subgroups according to BIS. T lymphocyte subsets and NK cell before anes-thesia, the end of surgery, 72 h after surgery were detected. Results CD3+, CD4+ T cell count, CD4+/CD8+ and NK cell of deep anesthesia subgroup and light anesthesia subgroups at the end of surgery were lower than before anesthesia and 72 h after operation (P<0.05). CD3+,CD4+T cell count, CD4+/CD8+and NK cell of deep anesthesia subgroup at the end of surgery were higher than light anesthesia subgroups (P<0.05). Conclusion Effect of deep anesthesia on perioperative cellular immune function of gastric cancer patients is less than light anesthesia.
