Clinical observation of hemoperfusion combined with plasma exchange in the treatment of severe organic phosphorus pesticide poisoning
- VernacularTitle:血液灌流联合血浆置换治疗重度有机磷农药中毒的临床观察
- Author:
Shimin ZOU
1
;
Tao HAN
Author Information
1. 新疆维吾尔自治区昌吉回族自治州中医医院急诊科
- Keywords:
Hemoperfusion (HP);
Plasma exchange (PE);
Organic phosphorus pesticide;
Poisoning
- From:
China Modern Doctor
2015;(11):79-81
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the clinical effects of hemoperfusion (HP) combined with plasma exchange (PE) in the treatment of severe organic phosphorus pesticide poisoning. Methods A total of 100 patients with severe organic phos-phorus pesticide poisoning who were admitted to our hospital from February 2012 to October 2014 were selected. Ac cording to patients' disease conditions, 50 patients were assigned to a treatment group (HP+HE), and another 50 patients were assigned to a control group (HP). Dosage of atropine and pralidoxime chloride, recovering time of CHE activity, average hospitalization days, coma time, complications and mortality rate between the two groups were compared. Re-sults Each observational index between the two groups was compared, and the results were significantly different (P<0.05). Effective rate in the treatment group was better than that in the control group, and the morality rate of 20.00%in the control group was significantly higher than that of 12.00% in the treatment group. Conclusion HP combined with PE is able to improve the curative effects of severe organic phosphorus pesticide poisoning significantly, reduce compli-cations and lower mortality rate.
