Clinical therapeutic effect of Tangbining granule in the treatment of dia-betic peripheral neuropathy and on oxidative stress
- VernacularTitle:糖痹宁颗粒治疗糖尿病周围神经病变临床疗效及其对机体氧化应激的影响
- Author:
Zhiqin GUO
1
;
Wenkui JIA
;
Yali GUO
;
Xiuping YANG
;
Jing LI
;
Jing ZHANG
Author Information
1. 山西中医学院中西医结合医院内分泌科
- Keywords:
Tangbining;
Diabetic peripheral neuropathy;
Oxidative stress
- From:
China Modern Doctor
2015;(10):126-129
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical curative effect of Tangbining granule in the treatment of diabetic periph-eral neuropathy syndrome of Yang deficiency and blood stasis type and the effect on oxidative stress. Methods selec-tion of diabetic peripheral neuropathy in patients with syndrome of Yang deficiency and blood stasis type, on the basis of the control group adds the clothing Tangbining granule, with symptom scores as the criterion of curative effect ob-servation of sugar,Tangbining granule in the treatment of diabetic peripheral neuropathy (DPN)effectiveness,safety,and observed before and after treatment with indicators of oxidative stress in the body superoxide dismutase enzyme(SOD)and malondialdehyde(MDA)changes. Results The total efficiency of the control group 70.37%,the total effec-tive rate of treatment group was 92.59%,there was significant difference between two groups (P<0.05); the SOD and MDA changes of the control group had no significant difference before and after the treatment, the SOD and MDA changes of the treatment group before and after treatment were statistically differences,and there was significant differ-ence in the change of MDA and SOD after treatment between two groups. There was no adverse reaction in two groups. Conclusion Tangbining granule in the treatment of diabetic peripheralneuropathy with Yang deficiency and blood stasis syndrome has exact curative effect,at the same time can improve oxidative stress in the body,without adverse reaction.
