Analysis of curative effect of cisplatin combined with gemcitabine and cis-platin plus paclitaxel in the treatment of advanced non-small cell lung cancer
- VernacularTitle:顺铂联合吉西他滨与顺铂联合紫杉醇治疗晚期非小细胞肺癌的疗效分析
- Author:
Yongtao WEN
1
;
Zhaobang WANG
;
Yiju ZHAO
;
Qiuting LIANG
;
Jie CAI
Author Information
1. 广东省东莞市第五人民医院呼吸内科
- Keywords:
Non-small cell lung cancer;
Advanced;
Cisplatin;
Gemcitabine;
Paclitaxel
- From:
China Modern Doctor
2015;(3):74-76
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the curative effect of cisplatin combined with gemcitabine and cisplatin plus pacli-taxel in the treatment of advanced non-small cell lung cancer. Methods All 100 patients with non-small cell lung can-cer in our hospital from January 2012 to January 2014 in our hospital, randomly divided into observation group (gemc-itabine+cisplatin, GP group) and control group (paclitaxel+cisplatin, TP group), each group had 50 cases, two groups of patients every 21 days for a cycle, observed curative effect after 2 cycles, toxic and adverse reaction were compared between the two groups. Results The effective rate of the observation group after treatment was 42.0%(21/50),was higher than that of the control group 40% (20/50), but there was no significant difference (P>0.05). Conclusion Cura-tive effect of cisplatin combined with gemcitabine and cisplatin plus paclitaxel in the treatment of advanced non-small cell lung cancer is similar, the poisonous side effect is different and can be tolerated, for the treatment of advanced non-small cell lung cancer treatment plan better.
