The effect of three dimensional conformal radiotherapy combined capecitabine in treatment of rectal cancer
- VernacularTitle:三维适形放疗同步联合卡培他滨治疗直肠癌的疗效观察
- Author:
Kaitai LIU
1
;
Huanle ZHANG
;
Miaozhen LU
Author Information
1. 宁波市医疗中心李惠利医院放疗科
- Keywords:
Rectal cancer;
Three-dimensional conformal radiotherapy;
Capecitabine;
Recurrence
- From:
China Modern Doctor
2015;(3):65-67
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of three dimensional conformal radiotherapy combined capecitabine in treatment of rectal cancer. Methods Sixty patients with advanced rectal carcinoma from January 2010 to January 2011 were selected, 32 cases with three dimensional conformal radiotherapy combined capecitabine establishment as the ob-servation group, 28 cases with simple radiotherapy establishment as the control group, the total effective rate, disease control rate, the rate of local recurrence, distant metastasis rate, adverse reaction rate were compared between two groups. Results After 4 cycles of therapy, the clinical total effective rate of observation group was 53.1%, the control group was 28.6%, there were significant differences (P<0.05). The disease control rate of observation group was 90.6%, the control group was 67.9%, there were significant differences(P<0.05). Compared with control group, the local recur-rence rate and the rate of distant metastasis of observation group had statistically significant difference (P<0.05). Con-clusion Concurrent three dimensional conformal radiotherapy combined with capecitabine in the treatment of rectal cancer has curative effect, good safety, can reduce the recurrence rate and distant metastasis rate and increase the sur-vival rate of patients.
