Study on the correlation between Kawasaki disease and mycoplasma pneumomiae
- VernacularTitle:川崎病与支原体感染的相关性研究
- Author:
Peiqin WANG
1
;
Fuguang RAO
;
Jianjun LUO
Author Information
1. 深圳市龙岗区妇幼保健院儿科
- Keywords:
Kawasaki disease;
Mycoplasma infection;
Coronary artery lesions;
Correlation
- From:
China Modern Doctor
2015;(3):41-43
- CountryChina
- Language:Chinese
-
Abstract:
Objective To invetigate the correlation between Kawasaki disease (KD) and mycoplasma pneumomiae (MP). Methods The medical records of 84 children diagnosed as KD in our hospital from March 2012 to February 2014 were retrospectively analyzed, and according to whether with mycoplasma infection or not ,they were divided into observation group and control group. The observation group included 43 cases with mycoplasma infection, and the control group in-cluded 41 KD patients without MP infection. White blood cell count (WBC), high sensitive C reactive protein (CRP), erythrocyte sedimentation rate (ESR), hemoglobin (HB), platelet count (PLT) were detected and analyzed in two groups. Patients of the two groups were compared in whether the existence of coronary artery lesions. Results Patients of the observation group without coronary artery injury accounted for 34.9%(15/43), significantly lower than that of the con trol group 58.5%(24/41), and the observation group with coronary lesions accounted for 65.1%(28/43), significantly higher than that of the control group 41.5%(17/41). The differences were statistically significant (P<0.05); CRP of the observation group was (68.9±14.7) mg/L, significantly higher than that of the control group (52.8±8.2) mg/L, and ESR of the observation group was (42.6 ±15.9) mm/h, significantly higher than that of the control group (21.6 ±6.1) mm/h. The differences were statistically significant (P<0.05). Conclusion MP is one of the causes of KD and has positive corre-lation with coronary artery injury of patients. The injury and inflammation reaction mediated by autoimmune reaction caused by MP is an important way to KD.
