Clinical research of transurethral resection combined with pirarubicin in-fusion in the treatment of superficial bladder tumor
- VernacularTitle:经尿道电切术联合吡柔比星灌注治疗浅表性膀胱肿瘤的临床研究
- Author:
Wenhao HU
1
;
Xiaobo ZHOU
Author Information
1. 宁波市鄞州人民医院泌尿外科
- Keywords:
Superficial bladder cancer;
Transurethral resection;
Pirarubicin;
Infusion therapy;
Recurrence rate
- From:
China Modern Doctor
2015;(3):32-34
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the curative effect of transurethral resection combined with pirarubicin infusion in the treatment of superficial bladder tumor. Methods From June 2010 to June 2012 in our hospital undergoing transurethral resection after treatment combined with pirarubicin instillation for the treatment of superficial bladder tumor in 32 cases , set up in the observation group, the otherunderwent transurethral resection after treatment with mitomycin irrigation in treatment of superficial bladder tumor in 30 cases, set up as the control group,1) comparison of the observation group group and control group, operation time,postoperative indwelling catheter time, hospitalization time; 2) complications and recurrence of the two groups after treatment. Results The two groups of patientswere a successful operation , TURBT operation time was 10-65 min. Two groups of intraoperative bleeding was less , the observation group 2 cases , control grouponly only 3 cases of postoperative bleeding obvious , reimplanted resectoscope were successful hemostasis. The operation time,postoperative indwelling catheter time, hospitalization time in the observation group compared with the control group, there was no significant difference (P>0.05). After treatment, liver and kidney function damage obvious and systemic reaction was not found in the two groups of patients , the number of cases of occurrence frequent micturition, dysuria and hematuria of the observation group was significantly less than that of the control group (P<0.05), and followed up 2 years, the main inspection items for B ultrasound, CT, cystoscopy, and no case of death in both two groups, the observation group was significantly lower than that of control group, the recurrence rate of recur-rent rate, with significant difference (P<0.05). The emergence of 6 months without recurrence after operation in the two groups, the observation group 1 case, control group 5 cases of recurrent patients were appeared in 9-12 months after operation, all non recurrence in situ. Conclusion Transurethral resection combined with pirarubicin instillation for the treatment of superficial bladder tumorexact curative effect, low recurrence rate, worthy of promotion and appli-cation.
