The relationship between serum betatrophin levels of newly diagnosed type 2 diabetes patients and insulin resistance
- VernacularTitle:初诊2型糖尿病患者血清betatrophin水平及其与胰岛素抵抗水平的关系
- Author:
Yunyang WANG
1
;
Di ZHANG
;
Jing DONG
;
Zhengyao JIANG
;
Xiaoqing LU
;
Yangang WANG
Author Information
1. 青岛大学临床医学院
- Keywords:
Type 2 diabetes;
Betatrophin;
Insulin resistance;
Triglyceride;
Free fatty acids
- From:
China Modern Doctor
2015;(3):4-6
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the association between serum betatrophin levels and insulin resistance in newly diagnosed type 2 diabetes patients. Methods A total of 31 healthy subjects (control group) and 35 newly-diagnosed type 2 diabetes patients(new T2DM group) were recruited. Serum betatrophin was detected with the methods of ELISA, insulin resistance was assessed with homeostasis model(HOMA-IR). Results The levels of betatrophin, free fatty acids, HOMA-IR, fasting plasma glucose, fasting serum insulin, high-density lipoprotein cholesterol and low-density lipoprotein cholesterol were significantly higher in group B than those in group A (P<0.05). Conclusion Insulin resis-tance leads to elevated serum levels of betatrophin in patients with newly diagnosed type 2 diabetes.
