Influence of epidural dexmedetomidine and sufentanil on epidural ropiva-caine anesthesia
- VernacularTitle:右美托咪定和舒芬太尼硬膜外给药对硬膜外罗哌卡因麻醉效果的影响
- Author:
Liang HE
1
;
Junmei XU
;
Tao HE
Author Information
1. 湖南省娄底市中心医院麻醉科
- Keywords:
Dexmedetomidine;
Remifentanil;
Epidural anesthesia;
Ropivacaine
- From:
China Modern Doctor
2014;(35):60-62
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of epidural dexmedetomidine (Dex) and sufentanil on ropivacaine epidu-ral anesthesia. Methods A total of 120 cases of ASA Ⅰ to Ⅱ patients used epidural anesthesia with ropivacaine for lower limb orthopedic surgery were randomly allocated into epidural anesthesia with ropivacaine+normal saline group, ropivacaine+sufentanil group, ropivacaine+dexmedetomidine group, the hemodynamic changes, sensory block onset time, the highest plane of sensory block, sensory block continuous time, completed motor block time before and after anesthe-sia drugs and occurrence of adverse reaction of nausea, itching, vomiting were observed. Results The sensory block on-set time, complete motor block time in the dexmedetomidine group were shorter than the other two groups, with signifi-cant difference (t=4.25, 4.59, 4.32, 3.82, 3.79, 4.23, P<0.05); The duration of sensory block was higher than that in the other two groups, with significant difference (t=6.24, 5.78, P<0.05); Hemodynamic changes and adverse reaction rate in each group had no significant difference (P>0.05). Conclusion Epidural DEX can enhance the epidu ral anesthesia effect of ropivacaine than sufentanil effectively, and it does not increase the incidence of adverse reaction.
