Specific IgG antibody responses in experimental cat metagonimiasis.
10.3347/kjp.1987.25.2.149
- Author:
Seung Yull CHO
1
;
Suk Il KIM
;
Shin Yong KANG
Author Information
1. Department of Parasitology, College fo Medicine, Chung-Ang University, Seoul 151, Korea.
- Publication Type:Original Article
- MeSH:
parasitolgy-helminth-trematoda;
cat;
metagonimiasis;
Metagonimus yokogawai;
IgG;
enzyme-linked immunosorbent assay
- From:The Korean Journal of Parasitology
1987;25(2):149-153
- CountryRepublic of Korea
- Language:English
-
Abstract:
In order to observe the feasibility of serologic diagnosis of metagonimiasis, saline extracts of metacercariae and 4-week old adults were prepared. Sera from 25 experimentally infected cats were collected from 3 days to 12 weeks after infection. Their levels of specific IgG antibody were measured by ELISA together with 3 sera from non-infected cats. Specific IgG antibody levels began to rise in 7 days after infection, reached their peak in 2-4 weeks and made a plateau thereafter. Cats infected with hundreds of adult worms showed minimal rise of the antibody level. Adult antigen was superior to metacercarial antigen in detecting the specific IgG antibody.