The clinical value of γ-IFN, ADA in the diagnosis and treatment of tu-berculous peritonitis
- VernacularTitle:γ-干扰素、腺苷脱氨酶在结核性腹膜炎诊治中的临床价值
- Author:
Xikun HUANG
1
;
Ling XIAO
;
Fuda HUANG
Author Information
1. 广东省中山市人民医院呼吸内科
- Keywords:
Tuberculous peritonitis;
Interferon-γ;
Adenosine deaminase
- From:
China Modern Doctor
2014;(30):13-15
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the clinic value of γ-IFN,ADA in diagnosis and treatment of tuberculous peritonitis. Methods The level of γ-IFN,ADA in pleural effusion of all the patients (29 cases of tuberculous peritonitis effulion and 22 cases of malignant ascites effusion) were detected and compared. Result The level and activity of tuberculous peritonitis group, interferon gamma, adenosine deaminase were higher in malignant ascites group (P<0.05).The combined detection of 2 indexes in the diagnosis of tuberculous peritonitis sensitivity was 86.2%, specificity 95.5%. Compared with the single detection of ADA, the sensitivity was similar, and the specificity increased. Conclusion Ascites effusion,γ-IFN and ADA all have the clinical significance on the identification between tuberculous peritonitis effusion and malignant ascites effusion, which can be used for differential diagnosis. At the same time, IFN-γand ADA examination can improve the diagnosis specificity of tuberculous pleural peritonitis.