Median effective target effect-site concentration of remifentanyl inhibiting cardiovascular response to tracheal intubation in women with preeclamp-sia under intravenous injection of labetalol
- VernacularTitle:拉贝洛尔降压下瑞芬太尼抑制子痫前期产妇气管插管反应的半数有效浓度
- Author:
Tao WANG
1
;
Zhongyou ZENG
;
Wangping ZHANG
;
Qun XU
;
Yinfa ZHANG
;
Fei XIAO
Author Information
1. 武警浙江省总队嘉兴医院麻醉科
- Keywords:
Remifentanil;
Propofol;
Labetalol;
Dose-response relationship
- From:
China Modern Doctor
2014;(29):63-65
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the median effective concentration (EC50) of remifentanyl inhibiting cardiovascular response to tracheal intubation in women with preeclampsia. Methods Thirty women with preeclampsia were enrolled in this study. The target Ce was set at 3 ng/mL. The positive cardiovascular response was defined as the blood pressure≥160/110 mmHg. The EC50 (95%confidence interva1) of cardiovascular responses to tracheal intubation was calculated by Probit analysis. Results EC50 (95% confidence interval) of remifentanyl inhibiting cardiovascular response to tracheal intubation was 1.93 (1.89~1.95) ng/mL. Conclusion EC50 of remifentanyl inhibiting cardiovascular response to tracheal intubation is 1.93 ng/mL in women with preeclampsia.
